A novel polymethylmethacrylate hydrophilic adhesive matrix intended for transdermal patch formulations
نویسندگان
چکیده
منابع مشابه
A Smart Patch for Transdermal Drug Delivery
Transdermal drug delivery of ibuprofen, a well known NSAID has sparked considerable research interest in the recent years. The hydrophobic nature of the drug as well as its water insolubility is a significant deterrent for its uptake through the skin and its bioavailability at the targeted site of pain/inflammation. This work addresses both concerns through a novel microemulsion formulation syn...
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A wearable adhesive skin patch for transdermal drug delivery is developed with bendable microneedles, dry adhesive and triboelectric energy harvester (TEH). The bendable microneedle array can overcome the needle breakage issue. The dry adhesive can realize a conformal attachment. The TEH can generate power when attached on flat skin or joint to power active components to be integrated in the fu...
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BACKGROUND Cholinesterase inhibitors have all been available in oral formulations, but a rivastigmine transdermal patch has now been developed and is approved in many countries worldwide for the treatment of mild-to-moderate Alzheimer's disease (AD) (including the USA, Latin America, Europe and Asia). OBJECTIVES To review the available pharmacokinetic data that supported the rationale behind ...
متن کاملDesign and in vitro evaluation of new drug-in-adhesive formulations of fentanyl transdermal patches.
The present research was designed to evaluate different matrix, drug-in-adhesive and reservoir formulations of fentanyl transdermal patches. The target was to design drug-in-adhesive patches (DIAPs); a full factorial design was used. Different types and amounts of liquid, pressure-sensitive adhesives (PSAs) were used and evaluated with respect to drug release and adhesive properties. A very sim...
متن کاملA Novel Patch-Based Digital Signature
In this paper a new patch-based digital signature (DS) is proposed. The proposed approach similar to steganography methods hides the secure message in a host image. However, it uses a patch-based key to encode/decode the data like cryptography approaches. Both the host image and key patches are randomly initialized. The proposed approach consists of encoding and decoding algorithms. The encodin...
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ژورنال
عنوان ژورنال: Drug Delivery
سال: 2010
ISSN: 1071-7544,1521-0464
DOI: 10.3109/10717541003667772